COPD Sherlock

This page is under construction.

Sherlock stands for SevERe earLy-Onset COPD. The aim is to include 580 persons in the cohort.

The cohort consists of the following groups:

• Non-COPD (ex-smokers)
• Non-COPD (current smokers)
• COPD Gold I/II (ex-smokers)
• COPD Gold I/II (current smokers)
• COPD Gold III/IV

Samples and measurements:

• Patient characteristics
• Pulmonary function tests
• CT-Thorax
• Bronchoscopy 
  • Nasal brushes
  • (Nasal) epithelial linning fluid
  • Bronchial wash
  • Bronchial biopsy
  • Bronchial brush
• Peripheral blood
• Sputum
• Urine 
• Faeces
• Volatile Organic Compounds (VOCs)